| | Day | Time | | Opponent | Score | | Record |
| November |
| | 5 | 5:30 PM | @ | Berea College | W-103-88 | | 1-0 |
| | 8 | 5:30 PM | vs. | Alice Lloyd College | W-82-59 | | 2-0 |
| * | 15 | 5:30 PM | @ | Montreat | W-91-63 | | 3-0 1-0 |
| | UVA-W: S. Helton-23 points, L. Collier-20 points MC: Jaime Gragg-16 points |
| * | 19 | 5:30 PM | @ | Brevard College | W-78-60 | | 4-0 2-0 |
| | UVa-W-LaShay Collier 21 pts., Sarah Helton 16 pts. |
| * | 23 | 2:00 PM | vs. | Bluefield | W-106-46 | | 5-0 3-0 |
| | UVa-W-LaShay Collier 25 pts., Sarah Helton 16 pts. |
| * | 29 | 5:30 PM | vs. | Union | W-81-56 | | 6-0 4-0 |
| December |
| | 2 | 3:00 PM | vs. | Midway College | W-54-53 | | 7-0 |
| | 2nd Annual Shootout in Shenandoah Tournament @ So. VA University |
| | 3 | | @ | Taylor University-Ft. Wayne | W-86-54 | | 8-0 |
| | Southern Virginia Tournament |
| * | 6 | 5:30 PM | @ | Tennessee Wesleyan | L-50-68 | | 8-1 4-1 |
| * | 9 | | @ | Milligan | L-59-73 | | 8-2 4-2 |
| | Milligan - Rikki Baughman & Kacie Letterman 17 pts each UVA-Wise - Chelsea Lee 16 pts Sarah Helton 13 pts |
| | 11 | 4:00 PM | @ | Pikeville | L-72-83 | | 8-3 |
| | 28 | 7:00 PM | vs. | Oklahoma Christian University | L-50-91 | | 8-4 |
| | South Padre Island Tournament - Oklahoma Christian 12th in NAIA DI |
| | 29 | 6:00 PM | vs. | New Jersey Institute of Technology | L-63-79 | | 8-5 |
| | South Padre Island Tournament |
| January |
| * | 6 | 5:30 PM | @ | Covenant College | W-72-59 | | 9-5 5-2 |
| | Sarah Helton 22 pts. & 10 rebs. (UVW) and Joanna Reitz 21 pts and 11 rebs. (CC) |
| * | 7 | 5:30 PM | @ | Bryan | L-51-61 | | 9-6 5-3 |
| * | 10 | 5:30 PM | vs. | Virginia Intermont | W-68-57 | | 10-6 6-3 |
| | UVa-W: Sarah Helton 26 pts. & 12 rebs., Chelsea Lee 17 pts. |
| | 12 | 6:30 PM | @ | Georgetown College | L-60-102 | | 10-7 |
| | UVa-W: Rachel Helton 19 pts., 5 3's |
| * | 14 | 2:00 PM | vs. | King College | W-76-67 | | 11-7 7-3 |
| | UVa-W: Rachel Helton 21 pts. |
| * | 17 | 5:30 PM | vs. | Montreat | W-81-59 | | 12-7 8-3 |
| | UVa-W: Sarah Helton 22 pts.; LaShay Collier 21 pts.; Mon: Jaime Gregg 16 pts. |
| * | 21 | 5:30 PM | vs. | Brevard College | W-79-65 | | 13-7 9-3 |
| | Brev: Holly Krogman 26 pts.; UVA-W: LaShay Collier 19 pts. |
| * | 24 | 5:30 PM | @ | Union | W-94-83 | | 14-7 10-3 |
| | UC: Susanna Todd scores 19 ... WISE: Sarah Helton nets 28 points, 12 rebounds |
| * | 26 | 5:30 PM | @ | Bluefield | W-82-56 | | 15-7 11-3 |
| * | 31 | 5:30 PM | vs. | Tennessee Wesleyan | W-65-60 | | 16-7 12-3 |
| February |
| | 2 | 5:00 PM | vs. | Kentucky Christian | W-64-61 | | 17-7 |
| | UVa-W: LaShay Collier 19 pts., Rachel Helton 14 pts. |
| * | 3 | | vs. | Milligan | W-70-64 | | 18-7 13-3 |
| | Mill: Stout & Letterman 14 pts.; UVA-W: Sarah Helton & Rachel Helton 16 pts. |
| | 7 | 5:30 PM | @ | Alice Lloyd College | W-79-56 | | 19-7 |
| | UVa-W: Sarah Helton 21 pts., LaShay Collier 17 pts. |
| * | 10 | 5:30 PM | vs. | Covenant College | W-71-68 | | 20-7 14-3 |
| | Cov: Joanna Reitz 19 pts.; UVa-W: LaShay Collier 22 pts., Sarah Helton 18 pts. |
| * | 11 | 4:00 PM | vs. | Bryan | L-66-74 | | 20-8 14-4 |
| | BRY: Brittany Swanson 31 pts.; UVa-W: Chelsea Lee 18 pts. |
| * | 14 | 5:30 PM | @ | Virginia Intermont | W-80-61 | | 21-8 15-4 |
| * | 18 | 2:00 PM | @ | King College | L-70-75 | | 21-9 15-5 |
| | 23 | 2:15 PM | vs. | Tennessee Wesleyan | W-76-71 (OT) | | 22-9 |
| | AAC Second Round Game |
| | 24 | 4:00 PM | vs. | Milligan | W-58-57 | | 23-9 |
| | AAC Semi-Final Game |
| | 25 | 6:00 PM | @ | King College | W-57-54 | | 24-9 |
| | AAC Championship |
| March |
| | 9 | 8:30 PM | vs. | Morningside College | L-62-82 | | 24-10 |
| | NAIA Championships |
